| Product Data | |
| Product Name | 9E10, Anti-Myc Monoclonal Antibody |
| Clone Name | 9E10 |
| Applications | FC, IF, IP, WB |
| Target | Myc tag |
| Host | Mouse |
| Clonality | Monoclonal |
| Immunogen | AEEQKLISEEDLLRKRREQLKHKLE conjugated to KLH, corresponding to C terminal amino acids 408-432 of human c-Myc |
| Isotype | IgG1 |
| Formulation | 0.64 mg/ml in PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | Lot dependent |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C. |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
| The use of this Antibodies has been cited in the following citations: |
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| Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation ,Wang, W;Qin, Y;Song, H;Wang, L;Jia, M;Zhao, C;Gong, M;Zhao, W;, Journal of immunology (Baltimore, Md. : 1950) 2021 ,PubMed ID 33963043 [MYC] |
| USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS ,Hou, J;Han, L;Zhao, Z;Liu, H;Zhang, L;Ma, C;Yi, F;Liu, B;Zheng, Y;Gao, C;, Nature communications 2021 ,PubMed ID 34016972 [MYC] |
| Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin ,Zhang, Y;Li, Y;Liu, P;Gong, D;Zhou, H;Li, W;Zhang, H;Zheng, W;Xu, J;Cheng, H;Zhang, X;Ke, Y;, Journal of extracellular vesicles 2021 ,PubMed ID 33732417 [MYC] |
| Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1 ,Li, X;Li, S;Li, B;Li, Y;Aman, S;Xia, K;Yang, Y;Ahmad, B;Wu, H;, NPJ precision oncology 2021 ,PubMed ID 33742100 [MYC] |
| Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling ,Zheng, Y;Zhuang, M;Han, L;Zhang, J;Nan, M;Zhan, P;Kang, D;Liu, X;Gao, C;Wang, P;, Signal Transduction and Targeted Therapy 2020 ,PubMed ID 33372174 [MYC] |
| Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P ,Liu, F;Zuo, X;Liu, Y;Deguchi, Y;Moussalli, MJ;Chen, W;Yang, P;Wei, B;Tan, L;Lorenzi, PL;Gao, S;Jaoude, JC;Mehdizadeh, A;Valentin, LA;Wei, D;Shureiqi, I;, Cell Rep 2020 ,PubMed ID 32814052 [MYC] |
| TAOK1 positively regulates TLR4-induced inflammatory responses by promoting ERK1/2 activation in macrophages ,Zhu, L;Yu, Q;Gao, P;Liu, Q;Luo, X;Jiang, G;Ji, R;Yang, R;Ma, X;Xu, J;Yuan, H;Zhou, J;An, H;, Mol. Immunol. 2020 ,PubMed ID 32344244 [MYC] |
| Downregulation of hippocampal SIRT6 activates AKT/CRMP2 signaling and ameliorates chronic stress-induced depression-like behavior in mice ,Li, W;Liu, X;Qiao, H;, Acta Pharmacol. Sin. 2020 ,PubMed ID 32265492 [MYC] |
| Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3 ,Thayyullathil, F;Cheratta, A;Pallichankandy, S;Subburayan, K;Tariq, S;Rangnekar, V;Galadari, S;, Biochimica et Biophysica Acta (BBA) – Molecular Cell Research 2020 ,PubMed ID 32135176 [MYC] |
| The Myc tag monoclonal antibody 9E10 displays highly variable epitope recognition dependent on neighboring sequence context ,Schüchner, S;Behm, C;Mudrak, I;Ogris, E;, Sci Signal 2020 ,PubMed ID 31992583 [MYC] |
| Ku80 negatively regulates the expression of OCT4 via competitive binding to SALL4 and promoting lysosomal degradation of OCT4 ,Zhao, B;Zheng, X;Tan, X;Ke, K;Wang, F;Wang, Y;Xing, X;Zhang, C;Hu, P;Lan, S;Li, Q;Huang, A;Liu, X;, Int. J. Biochem. Cell Biol. 2019 ,PubMed ID 31816404 [MYC] |
| NOD1 inhibits proliferation and enhances response to chemotherapy via suppressing SRC-MAPK pathway in hepatocellular carcinoma ,Ma, X;Qiu, Y;Zhu, L;Zhao, Y;Lin, Y;Ma, D;Qin, Z;Sun, C;Shen, X;Li, T;Han, L;, J. Mol. Med. 2019 ,PubMed ID 31872284 [MYC] |
| Mink Enteritis Virus Infection Induces Mitochondrion-mediated Apoptosis by the Viral Nonstructural Protein 1 ,Lin, P;Cheng, Y;Song, S;Qiu, J;Yi, L;Cao, Z;Li, J;Cheng, S;Wang, J;, J. Virol. 2019 ,PubMed ID 31484746 [MYC] |
| Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or α-synuclein, is localized to the mitochondrial matrix ,Osuagwu, N;Dölle, C;Tzoulis, C;, PLoS ONE 2019 ,PubMed ID 31323073 [MYC] |
| Regulation of dendrite morphology and excitatory synapse formation by zDHHC15 ,Shah, BS;Shimell, JJ;Bamji, SX;, J. Cell. Sci. 2019 ,PubMed ID 31189538 [MYC] |
| Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease ,Ciappelloni, S;Bouchet, D;Dubourdieu, N;Boué-Grabot, E;Kellermayer, B;Manso, C;Marignier, R;Oliet, SHR;Tourdias, T;Groc, L;, Cell Rep 2019 ,PubMed ID 31242419 [MYC] |
| TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression ,Qiu, Y;Liu, P;Ma, X;Ma, X;Zhu, L;Lin, Y;You, Y;Yu, W;Ma, D;Sun, C;Qin, Z;Zhao, Y;Shi, J;Han, L;, Biochim Biophys Acta Mol Cell Res 2019 ,PubMed ID 31176697 [MYC] |
| Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4+ T cells by degrading viral Gag polyprotein ,Liang, G;Zhao, L;Qiao, Y;Geng, W;Zhang, X;Liu, M;Dong, J;Ding, H;Sun, H;Shang, H;, Nat. Immunol. 2019 ,PubMed ID 31061530 [MYC] |
| USP19 Inhibits TNF-α- and IL-1β-Triggered NF-κB Activation by Deubiquitinating TAK1 ,Lei, CQ;Wu, X;Zhong, X;Jiang, L;Zhong, B;Shu, HB;, J. Immunol. 2019 ,PubMed ID 31127032 [MYC] |
| Glia maturation factor-γ regulates murine macrophage iron metabolism and M2 polarization through mitochondrial ROS ,Aerbajinai, W;Ghosh, MC;Liu, J;Kumkhaek, C;Zhu, J;Chin, K;Rouault, TA;Rodgers, GP;, Blood Adv 2019 ,PubMed ID 30971398 [MYC] |
| Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats ,Li, X;Jin, X;Sharma, S;Liu, X;Zhang, J;Niu, Y;Li, J;Li, Z;, BioRxiv 2019 [MYC] |
| Escherichia coli as a platform for the study of phosphoinositide biology ,Botero, S;Chiaroni-Clarke, R;Simon, SM;, Sci Adv 2019 ,PubMed ID 30944849 [MYC] |
| Phosphatase Shp2 exacerbates intestinal inflammation by disrupting macrophage responsiveness to interleukin-10 ,Xiao, P;Zhang, H;Zhang, Y;Zheng, M;Liu, R;Zhao, Y;Zhang, X;Cheng, H;Cao, Q;Ke, Y;, J. Exp. Med. 2019 ,PubMed ID 30610104 [MYC] |
| Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival ,Losada, A;Muñoz-Alonso, MJ;Martínez-Díez, M;Gago, F;Domínguez, JM;Martínez-Leal, JF;Galmarini, CM;, Br. J. Cancer 2018 ,PubMed ID 30420615 [MYC] |
| Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor ,Zhou, X;Xu, M;Zeng, W;Chen, Z;Lu, G;Gong, Y;Finnell, RH;Xiao, H;Qiao, B;Wang, H;, Cell Death Discov 2018 ,PubMed ID 30062063 [MYC] |
| UBXN3B positively regulates STING-mediated antiviral immune responses ,Yang, L;Wang, L;Ketkar, H;Ma, J;Yang, G;Cui, S;Geng, T;Mordue, DG;Fujimoto, T;Cheng, G;You, F;Lin, R;Fikrig, E;Wang, P;, Nat Commun 2018 ,PubMed ID 29899553 [MYC] |
| TRIM50 suppressed hepatocarcinoma progression through directly targeting SNAIL for ubiquitous degradation ,Ma, X;Ma, X;Qiu, Y;Zhu, L;Lin, Y;You, Y;Ma, D;Qin, Z;Sun, C;Zhao, Y;Sun, Y;Han, L;, Cell Death Dis 2018 ,PubMed ID 29789583 [MYC] |
| Expression of the onconeural protein CDR1 in cerebellum and ovarian cancer ,Totland, C;Kråkenes, T;Mazengia, K;Haugen, M;Vedeler, C;, Oncotarget 2018 ,PubMed ID 29844866 [MYC] |
| Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation ,Bao, Q;Li, C;Xu, C;Zhang, R;Zhao, K;Duan, Z;, Gene 2017 ,PubMed ID 29197592 [Myc] |
| Intracellular mature IL-37 suppresses tumor metastasis via inhibiting Rac1 activation ,Li, Y;Zhao, M;Guo, C;Chu, H;Li, W;Chen, X;Wang, X;Li, Y;Jia, Y;Koussatidjoa, S;Zhu, F;Wang, J;Wang, X;Wang, Q;Zhao, W;Shi, Y;Chen, W;Zhang, L;, Oncogene 2017 ,PubMed ID 29106392 [Myc] |
| 25-Hydroxycholesterol Inhibition of Lassa Virus Infection through Aberrant GP1 Glycosylation ,Shrivastava-Ranjan, P;Bergeron, É;Chakrabarti, AK;Albariño, CG;Flint, M;Nichol, ST;Spiropoulou, CF;, MBio 2016 ,PubMed ID 27999160 [MYC] |
| Phosphorylation of NFAT3 by CDK3 induces cell transformation and promotes tumor growth in skin cancer ,Xiao, T;Zhu, JJ;Huang, S;Peng, C;He, S;Du, J;Hong, R;Chen, X;Bode, AM;Jiang, W;Dong, Z;Zheng, D;, Oncogene 2016 ,PubMed ID 27893713 [MYC] |
| The Role and Regulation of Mitochondrial Dynamics in Cisplatin Resistance in Human Gynecologic Cancer Cells ,Kong, B;, Thesis Jun 2015 [Myc] |
| Identification and Characterization of Cyprinid Herpesvirus-3 (CyHV-3) Encoded MicroRNAs ,Donohoe, OH;Henshilwood, K;Way, K;Hakimjavadi, R;Stone, DM;Walls, D;, PLoS ONE May 2015 ,PubMed ID 25928140 [MYC] |
| Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes ,Lauranzano, E;Pozzi, S;Pasetto, L;Stucchi, R;Massignan, T;Paolella, K;Mombrini, M;Nardo, G;Lunetta, C;Corbo, M;Mora, G;Bendotti, C;Bonetto, V;, Brain Feb 2015 ,PubMed ID 25678563 [Myc] [IP] |
| Huntingtin-associated protein 1 interacts with breakpoint cluster region protein to regulate neuronal differentiation ,Huang, PT;Chen, CH;Hsu, IU;Salim, SA;Kao, SH;Cheng, CW;Lai, CH;Lee, CF;Lin, YF;, PLoS ONE Feb 2015 ,PubMed ID 25671650 [Myc] [IF] |
| SHP2 Positively Regulates TGFß1-induced Epithelial-mesenchymal Transition Modulated by Its Novel Interacting Protein Hook1 ,Li, S;Wang, L;Zhao, Q;Liu, Y;He, L;Xu, Q;Sun, X;Teng, L;Cheng, H;Ke, Y;, J. Biol. Chem. Oct 2014 ,PubMed ID 25331952 [Myc] [IP] |
| p53 is required for cisplatin-induced processing of the mitochondrial fusion protein L-Opa1 that is mediated by the mitochondrial metallopeptidase Oma1 in Gynecologic Cancers ,Kong, B;Wang, Q;Fung, E;Xue, K;Tsang, BK;, J. Biol. Chem. Aug 2014 ,PubMed ID 25112877 [Myc] [WB] |
| Holocarboxylase synthetase interacts physically with the nuclear receptor corepressor, histone deacetylase 1, and a novel splicing variant of histone deacteylase 1 to repress repeats ,Liu, D;Zempleni, J;, Biochem. J. May 2014 ,PubMed ID 24840043 [Myc] [IP] |
| Novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation ,Macri, V;Mahida, SN;Zhang, ML;Sinner, MF;Dolmatova, EV;Tucker, NR;McLellan, M;Shea, MA;Milan, DJ;Lunetta, KL;Benjamin, EJ;Ellinor, PT;, Heart Rhythm Mar 2014 ,PubMed ID 24607718 [anti-myc] [IF] |
| The PTH-Gαs-PKA cascade controls αNAC localization to regulate bone mass ,Pellicelli, M;Miller, JA;Arabian, A;Gauthier, C;Akhouayri, O;Wu, JY;Kronenberg, HM;St-Arnaud, R;, Mol. Cell. Biol., Feb 2014. ,PubMed ID 24550008 [anti-MYC] [WB] |
| From Histone Modification to Gene Repression: Epigenetic Regulation by Holocarboxylase Synthetase-containing Repression Complex and FAD-dependent Lysine … ,Liu, D;, Thesis . March 2014 [MYC] [IP] |
| Glia maturation factor- mediates neutrophil chemotaxis ,Wulin Aerbajinai, Lunhua Liu, Kyung Chin, Jianqiong Zhu, Carole A. Parent, and Griffin P. Rodgers, J. Leukoc. Biol., Sep 2011; 90: 529 – 538. ,PubMed ID 21653232 [MYC] [IP] |
| Mechanism of Down-regulation of RNA Polymerase III-transcribed Non-coding RNA Genes in Macrophages by Leishmania ,Tanu Rana, Smita Misra, Mukul K. Mittal, Anitra L. Farrow, Keith T. Wilson, MacRae F. Linton, Sergio Fazio, Ian M. Willis, and Gautam Chaudhuri, J. Biol. Chem., Feb 2011; 286: 6614 – 6626 ,PubMed ID 21149457 [MYC] [IP] |